منابع مشابه
Osteoimmunology and osteoporosis
The concept of osteoimmunology is based on growing insight into the links between the immune system and bone at the anatomical, vascular, cellular, and molecular levels. In both rheumatoid arthritis (RA) and ankylosing spondylitis (AS), bone is a target of inflammation. Activated immune cells at sites of inflammation produce a wide spectrum of cytokines in favor of increased bone resorption in ...
متن کاملOsteoimmunology and Beyond
OBJECTIVE Osteoimmunology investigates interactions between skeleton and immune system. In the light of recent discoveries in this field, a new reading register of osteoporosis is actually emerging, in which bone and immune cells are strictly interconnected. Osteoporosis could therefore be considered a chronic immune mediated disease which shares with other age related disorders a common inflam...
متن کاملOsteoimmunology and nutritional science.
The concept of osteoimmunology was established more than a decade ago and is based on the reciprocal relationship between immune and bone cells. This way of looking to these two organs skeletal and immune system, has resulted in the development of clinical therapeutics for seemingly disparate but linked by the common themes of inflammation and bone remodeling. 1 Osteoimmunology includes osteopo...
متن کاملOsteoimmunology: A Brief Introduction
Recent investigations have demonstrated extensive reciprocal interactions between the immune and skeletal systems, resulting in the establishment of osteoimmunology as a cross-disciplinary field. Here we highlight core concepts and recent advances in this emerging area of study.
متن کاملOsteoimmunology in rheumatic diseases
This review summarizes the recent advances of osteoimmunology, a new research field that investigates the interaction of the immune system with the skeleton. Osteoimmunology has contributed significantly to the understanding of joint destruction in rheumatoid arthritis and other forms of arthropathies. In particular, the molecular regulation of osteoclast formation and its control by proinflamm...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cell Metabolism
سال: 2015
ISSN: 1550-4131
DOI: 10.1016/j.cmet.2015.02.001